Cis-(1R,3S)-3-aMino-cyclohexanol hydrochloride - Names and Identifiers
Name | (1R,3S)-3-Aminocyclohexanol
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Synonyms | (1R,3S) (1R,3S)-3-AMINOCYCLOHEXANOL (1R,3S)-3-Aminocyclohexanol (1R,3S)-3-aminocyclohexan-1-ol Cyclohexanol, 3-amino-, (1R,3S)- Cis-(1R,3S)-3-aMino-cyclohexanol hydrochloride
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CAS | 1110772-22-9
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InChI | InChI=1S/C6H13NO/c7-5-2-1-3-6(8)4-5/h5-6,8H,1-4,7H2/t5-,6+/m0/s1 |
Cis-(1R,3S)-3-aMino-cyclohexanol hydrochloride - Physico-chemical Properties
Molecular Formula | C6H13NO
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Molar Mass | 115.17 |
Density | 1.037±0.06 g/cm3(Predicted) |
Boling Point | 201.1±33.0 °C(Predicted) |
pKa | 15.09±0.40(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Cis-(1R,3S)-3-aMino-cyclohexanol hydrochloride - Introduction
(1R,3S)-3-aminocyclohexanol is a chiral organic compound with the formula C6H13NO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(1R,3S)-3-aminocyclohexanol is a solid, and its appearance is white crystal or powder. It has two chiral centers, so there are four possible stereoisomers. Its optical rotation is positive and its optical rotation is 10.2 °(c = 1, ethanol). The compound is sparingly soluble in water and soluble in ethanol and other organic solvents.
Use:
(1R,3S)-3-aminocyclohexanol is widely used in the field of medicine. As a chiral intermediate, it is often used in the preparation of active forms of drugs in the synthesis of drugs. It is also used for the preparation of aminocyclohexane-containing compounds which have important applications in the agrochemical and pharmaceutical fields.
Preparation Method:
The preparation method of (1R,3S)-3-aminocyclohexanol can be achieved through various routes. A common method is to use 1,2-cyclohexanediol acetate chloride to obtain (1R,3S)-3-aminocyclohexanol by reduction. In this process, the hydroxyl moiety is substituted with an amino group.
Safety Information:
Last Update:2024-04-09 20:49:11